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WEE1-IN-10

WEE1-IN-10 (compound 77) is a Wee1 kinase inhibitor. WEE1-IN-10 shows inhibitory activity on LOVO cell growth, with an IC50 of 0.524 μM. WEE1-IN-10 can be used for the research of diseases caused by abnormal activity of Wee1[1].

Product Specifications

CAS Number

2226938-19-6

UNSPSC

12352005

Target

Wee1

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/wee1-in-10.html

Purity

99.32

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

CC1=C(N2C[C@H](C)N(C)[C@H](C)C2)C=CC(NC3=NC=C4C(N5C(N(C6=C(Cl)C=CC=C6Cl)C4=O)=NCC5)=N3)=C1

Molecular Formula

C28H30Cl2N8O

Molecular Weight

565.50

References & Citations

[1]CAI Suixiong, et al. 8,9-dihydroimidazole[1,2-a]pyrimido[5,4-e]pyrimidine-5 (6h) -ketone compound. Patent. WO2018090939A1.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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