WEE1-IN-10
WEE1-IN-10 (compound 77) is a Wee1 kinase inhibitor. WEE1-IN-10 shows inhibitory activity on LOVO cell growth, with an IC50 of 0.524 μM. WEE1-IN-10 can be used for the research of diseases caused by abnormal activity of Wee1[1].
Product Specifications
CAS Number
2226938-19-6
UNSPSC
12352005
Target
Wee1
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/wee1-in-10.html
Purity
99.32
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
CC1=C(N2C[C@H](C)N(C)[C@H](C)C2)C=CC(NC3=NC=C4C(N5C(N(C6=C(Cl)C=CC=C6Cl)C4=O)=NCC5)=N3)=C1
Molecular Formula
C28H30Cl2N8O
Molecular Weight
565.50
References & Citations
[1]CAI Suixiong, et al. 8,9-dihydroimidazole[1,2-a]pyrimido[5,4-e]pyrimidine-5 (6h) -ketone compound. Patent. WO2018090939A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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