(5E,9E,13E) -Teprenone

(5E,9E,13E) -Teprenone ((5E,9E,13E) -Geranylgeranylacetone) is an isomer of Teprenone with antiulcer activity. (5E,9E,13E) -Teprenone induces transcriptional activation of HSP genes that may increase gastric mucosal defense at conditions of stress[1].

Product Specifications

CAS Number

[3796-63-2]

Product Name Alternative

(5E,9E,13E) -Geranylgeranylacetone

UNSPSC

12352211

Target

HSP

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/5e-9e-13e-teprenone.html

Purity

99.88

Solubility

DMSO : 5 mg/mL (ultrasonic)

Smiles

CC(CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)\C)=O

Molecular Formula

C23H38O

Molecular Weight

330.56

References & Citations

[1]Hirakawa T, et al. Geranylgeranylacetone induces heat shock proteins in cultured guinea pig gastric mucosal cells and rat gastric mucosa. Gastroenterology. 1996 Aug;111 (2) :345-57.