SPAA-52
Product Specifications
UNSPSC Description
SPAA-52 is an orally active, competitive and reversible low-molecular-weight protein tyrosine phosphatase (LMW-PTP) inhibitor (IC50=4 nM, Ki=1.2 nM). SPAA-52 can be used in diabete research[1].
Target Antigen
Phosphatase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/spaa-52.html
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=S(O)(NC(NC1=CC(Br)=C(C)C(Br)=C1)=O)=O
Molecular Weight
388.03
References & Citations
[1]He R, et al. Structure-Based Design of Active-Site-Directed, Highly Potent, Selective, and Orally Bioavailable Low-Molecular-Weight Protein Tyrosine Phosphatase Inhibitors. J Med Chem. 2022 Oct 5.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-151591/SPAA-52-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-151591/SPAA-52-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2837000-75-4
Available Sizes
Curated Selection
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