THP-PEG4-Pyrrolidine (N-Me) -CH2OH
THP-PEG4-Pyrrolidine (N-Me) -CH2OH is a PEG-based PROTAC linker can be used in the synthesis of PROTAC K-Ras Degrader-1 (HY-129523) [1].
Product Specifications
CAS Number
[2378261-81-3]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/thp-peg4-pyrrolidine-n-me-ch2oh.html
Purity
95.0
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
OC[C@@H]1C[C@H](CN1C)OCCOCCOCCOCCOC2CCCCO2
Molecular Formula
C19H37NO7
Molecular Weight
391.50
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
References & Citations
[1]CREW, Andrew P., et al. MODULATORS OF PROTEOLYSIS AND ASSOCIATED METHODS OF USE. WO2019195609A2.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PEG Linkers
Available Sizes
Curated Selection
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