Biotin-C4-amide-C5-NH2

Biotin-C4-amide-C5-NH2 is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1].

Product Specifications

CAS Number

[151294-96-1]

UNSPSC

12352203

Hazard Statement

H315, H319

Target

ADC Linker

Type

ADC Related

Related Pathways

Antibody-drug Conjugate/ADC Related

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/biotin-c4-amide-c5-nh2.html

Purity

95.0

Solubility

10 mM in DMSO

Smiles

NCCCCNC(CCCC[C@@H]1SCC([H])([C@@]1(N2)[H])NC2=O)=O

Molecular Formula

C14H26N4O2S

Molecular Weight

314.45

Precautions

H315, H319

References & Citations

[1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16 (5) :315-337.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Scientific Category

ADC Related

Clinical Information

No Development Reported

Isoform

Cleavable Linker

Available Sizes

Curated Selection

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