Biotin-C4-amide-C5-NH2
Biotin-C4-amide-C5-NH2 is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1].
Product Specifications
CAS Number
[151294-96-1]
UNSPSC
12352203
Hazard Statement
H315, H319
Target
ADC Linker
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/biotin-c4-amide-c5-nh2.html
Purity
95.0
Solubility
10 mM in DMSO
Smiles
NCCCCNC(CCCC[C@@H]1SCC([H])([C@@]1(N2)[H])NC2=O)=O
Molecular Formula
C14H26N4O2S
Molecular Weight
314.45
Precautions
H315, H319
References & Citations
[1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16 (5) :315-337.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Cleavable Linker
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS1223740-01 0.02 mg (E-Coli)
Recombinant Bacillus subtilis Regulatory protein DegR (degR)
Ask
View Details