Biotin-C4-amide-C5-NH2
Biotin-C4-amide-C5-NH2 is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1].
Product Specifications
CAS Number
[151294-96-1]
UNSPSC
12352203
Hazard Statement
H315, H319
Target
ADC Linker
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/biotin-c4-amide-c5-nh2.html
Purity
95.0
Solubility
10 mM in DMSO
Smiles
NCCCCNC(CCCC[C@@H]1SCC([H])([C@@]1(N2)[H])NC2=O)=O
Molecular Formula
C14H26N4O2S
Molecular Weight
314.45
Precautions
H315, H319
References & Citations
[1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16 (5) :315-337.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Cleavable Linker
Available Sizes
Curated Selection
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