3-Acetyldeoxynivalenol-13C17

3-Acetyldeoxynivalenol-13C17 is the 13C labeled 3-Acetyldeoxynivalenol (HY-N6685) [1]. 3-Acetyldeoxynivalenol, a trichothecene mycotoxin deoxynivalenol (DON) acetylated derivative[2], is a blood-brain barrier (BBB) permeable mycotoxin[3].

Product Specifications

CAS Number

[1217476-81-7]

UNSPSC

12352005

Hazard Statement

H225, H302+H312+H332, H319

Target

Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Others

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/3-acetyldeoxynivalenol-13c17.html

Concentration

70.38 μM * 1.2 mL in Acetonitrile

Purity

99.0

Solubility

10 mM in DMSO

Smiles

[13CH3][13C@]12[13C@@]3([13C@@]([H])([13C@H](O[13C]([13CH3])=O)[13CH2]2)O[13C@]4([13C@]1([13CH2]O)[13C@H](O)[13C]([13C]([13CH3])=[13CH]4)=O)[H])[13CH2]O3

Molecular Formula

13C17H22O7

Molecular Weight

355.23

Precautions

H225, H302+H312+H332, H319

References & Citations

[1]Kadota T, et al. Comparative study of deoxynivalenol, 3-acetyldeoxynivalenol, and 15-acetyldeoxynivalenolon intestinal transport and IL-8 secretion in the human cell line Caco-2. Toxicol In Vitro. 2013 Sep;27 (6) :1888-95.|[2]Behrens M, et al. Blood-Brain Barrier Effects of the Fusarium Mycotoxins Deoxynivalenol, 3Acetyldeoxynivalenol, and Moniliformin and Their Transfer to the Brain. PLoS One. 2015 Nov 23;10 (11) :e0143640.|[3]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-220.