Sodium gualenate

Sodium gualenate (Guaiazulenesulfonate sodium) is a hydrophilic derivative of guaiazulene with excellent anti-inflammatory and wound-healing effects mainly used for the treatment of duodenal ulcer, gastric ulcer and gastritis.

Product Specifications

CAS Number

[6223-35-4]

Product Name Alternative

Guaiazulenesulfonate sodium

UNSPSC

12352005

Hazard Statement

H315-H319-H335

Target

Drug Derivative

Type

Reference compound

Related Pathways

Others

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/Sodium_gualenate.html

Purity

98.0

Solubility

DMSO : 25 mg/mL (ultrasonic) |H2O : 6.25 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=S(C1=C2C(C)=CC=C(C(C)C)C=C2C(C)=C1)(O[Na])=O

Molecular Formula

C15H17NaO3S

Molecular Weight

300.35

Precautions

P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362-P403+P233-P405-P501

References & Citations

[1]Nakamichi K, et al. Stabilization of sodium guaiazulene sulfonate in granules for tableting prepared using a twin-screw extruder. Eur J Pharm Biopharm. 2003 Nov;56 (3) :347-54.|[2]Cao T, et al. Synthesis and Biological Evaluation of 3, 8-dimethyl-5-isopropylazulene Derivatives as Anti-gastric Ulcer Agent. Chem Biol Drug Des. 2016 Aug;88 (2) :264-71.