NOD1 antagonist-1
NOD1 antagonist-1 (compound 37) exhibits an antagonistic activity towards NOD1 and a weak NOD1/NOD2 selectivity, with IC50s of 9.18 μM and 20.8 μM, respectively[1].
Product Specifications
UNSPSC
12352005
Target
NOD-like Receptor (NLR)
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/nod1-antagonist-1.html
Solubility
10 mM in DMSO
Smiles
CC1=CC=C(S(N2C3=CC=CC=C3C(N4CCN(CC4)C)=C2NC(C)(C)C)(=O)=O)C=C1
Molecular Formula
C24H32N4O2S
Molecular Weight
440.60
References & Citations
[1]Russo C, et al., Discovery of 2,3-Diaminoindole Derivatives as a Novel Class of NOD Antagonists. J Med Chem. 2024 Feb 1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
NOD1; NOD2
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