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CK-7 Polyclonal Antibody

Product Specifications

Background

Keratins are a large family of proteins that form the intermediate filament cytoskeleton of epithelial cells, which are classified into two major sequence types. Type I keratins are a group of acidic intermediate filament proteins, including K9–K23, and the hair keratins Ha1–Ha8. Type II keratins are the basic or neutral courterparts to the acidic type I keratins, including K1–K8, and the hair keratins, Hb1–Hb6. KRT7, also named as cytokeratin 7, is one member of type II basic cytokeratin. It is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels, and their neoplasms. KRT7 is marker of epithelial tissues, but not present in carcinomas of stratified squamous cell origin.This antibody is specifically against KRT7.

Abbreviation

CK-7

UniProt

Q9DCV7

Host

Rabbit

Reactivity

Human; Mouse

Immunogen

Recombinant Mouse Krt7 protein expressed by E.coli

Target

CK 7; Cytokeratin 7; D15Wsu77e; K2C7; K7; Keratin 7; Keratin type II cytoskeletal 7; Krt2-7; MGC11625; Sarcolectin; Type II mesothelial keratin K7

Clonality

Polyclonal

Conjugation

Unconjugated

Applications

WB; IHC

Field of Research

Cancer; Signal Transduction

Purification

Antigen Affinity Purification

Concentration

1 mg/mL

Dilution

WB 1:500-1:2000; IHC 1:250-1:500

Buffer

PBS with 0.02% sodium azide,1% protective protein and 50% glycerol, pH7.4

Shipping Conditions

The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

Storage Conditions

Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

Calculated Molecular Weight

51 kDa

Observed Molecular Weight

51 kDa

Isotype

IgG

Available Sizes

Frequently Asked Questions

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