α-Tocopherol phosphate (disodium)

α-Tocopherol phosphate disodium is an antioxidant that protects against long-wave UVA1 induced cell death and scavenge UVA1 induced ROS in a skin cell model. α-Tocopherol phosphate disodium exhibits angiogenesis-promoting activity[1][2].

Product Specifications

CAS Number

[60934-46-5]

Product Name Alternative

Alpha-Tocopherol phosphate (disodium) ; TocP (disodium) ; Vitamin E phosphate (disodium)

UNSPSC

12352200

Hazard Statement

H302, H315, H319, H335

Target

Apoptosis; Reactive Oxygen Species (ROS)

Type

Biochemical Assay Reagents

Related Pathways

Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Applications

Neuroscience-Neurodegeneration

Field of Research

Cardiovascular Disease; Cancer

Assay Protocol

https://www.medchemexpress.com/α-tocopherol-phosphate-disodium.html

Purity

98.01

Solubility

DMSO : 4 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

CC1=C2C(CC[C@](C)(O2)CCC[C@H](C)CCC[C@H](C)CCCC(C)C)=C(C(OP(O[Na])(O[Na])=O)=C1C)C

Molecular Formula

C29H49Na2O5P

Molecular Weight

554.65

Precautions

H302, H315, H319, H335

References & Citations

[1]Saleh MM, et al. The photoprotective properties of α-tocopherol phosphate against long-wave UVA1 (385 nm) radiation in keratinocytes in vitro. Sci Rep. 2021 Nov 17;11 (1) :22400.|[2]Wu Z, et al. α-Tocopherol, especially α-tocopherol phosphate, exerts antiapoptotic and angiogenic effects on rat bone marrow-derived endothelial progenitor cells under high-glucose and hypoxia conditions. J Vasc Surg. 2018 Apr;67 (4) :1263-1273.e1.