NITD-688
NITD-688 is an orally active pan-serotype inhibitor of the dengue virus NS4B protein. NITD-688 can be used in the research of dengue virus (DENV) [1].
Product Specifications
CAS Number
[2407227-31-8]
Product Name Alternative
EYU-688
UNSPSC
12352005
Target
Dengue Virus; Flavivirus; Virus Protease
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/nitd-688.html
Concentration
10mM
Purity
98.04
Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
N#CC(C(CN1CC2CCCCC2)=C(CC(C)1C)S3)=C3NC(CC(C=C4)=CC=C4[S](N)(=O)=O)=O
Molecular Formula
C25H32N4O3S2
Molecular Weight
500.68
References & Citations
[1]Moquin SA, et al. NITD-688, a pan-serotype inhibitor of the dengue virus NS4B protein, shows favorable pharmacokinetics and efficacy in preclinical animal models. Sci Transl Med. 2021 Feb 3;13 (579) :eabb2181.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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