Apamin
Product Specifications
UNSPSC Description
Apamin (Apamine) is an 18 amino acid peptide neurotoxin found in apitoxin (bee venom), is known as a specifically selective blocker of Ca2+-activated K+ (SK) channels and exhibits anti-inflammatory and anti-fibrotic activity[1].
Target Antigen
Potassium Channel
Type
Peptides
Related Pathways
Membrane Transporter/Ion Channel
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/Apamin.html
Purity
99.71
Solubility
H2O : 100 mg/mL (ultrasonic)
Smiles
O=C([C@@H](N)CSSC[C@H](NC1=O)C(N[C@H](C(N[C@H](C(N[C@H]2CCCNC(N)=N)=O)CCCNC(N)=N)=O)C)=O)N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N3[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H]1CC(C)C)=O)C)=O)[C@@H](C)O)=O)CCC(O)=O)=O)CCC3)=O)C)=O)CCCCN)=O)CSSC[C@H](NC2=O)C(N[C@H](C(N[C@H](C(N[C@H](C(N)=O)CC4=CNC=N4)=O)CCC(N)=O)=O)CCC(N)=O)=O)=O)CC(N)=O
Molecular Weight
2027.34
References & Citations
[1]Kim JY, et al. Apamin suppresses biliary fibrosis and activation of hepatic stellate cells. Int J Mol Med. 2017 May;39(5):1188-1194.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-P0256/Apamin-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P0256/Apamin-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
24345-16-2
Available Sizes
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