Apamin
Apamin (Apamine) is an 18 amino acid peptide neurotoxin found in apitoxin (bee venom), is known as a specifically selective blocker of Ca2+-activated K+ (SK) channels and exhibits anti-inflammatory and anti-fibrotic activity[1].
Product Specifications
CAS Number
24345-16-2
Product Name Alternative
Apamine
UNSPSC
12352209
Hazard Statement
H302, H315, H319, H335
Target
Potassium Channel
Type
Peptides
Related Pathways
Membrane Transporter/Ion Channel
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/Apamin.html
Purity
99.96
Solubility
H2O : 100 mg/mL (ultrasonic)
Smiles
Molecular Formula
C79H131N31O24S4
Molecular Weight
2027.34
Precautions
H302, H315, H319, H335
References & Citations
[1]Kim JY, et al. Apamin suppresses biliary fibrosis and activation of hepatic stellate cells. Int J Mol Med. 2017 May;39 (5) :1188-1194.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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