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L-Palmitoylcarnitine (TFA)

L-Palmitoylcarnitine TFA, a long-chain acylcarnitine and a fatty acid metabolite, accumulates in the sarcolemma and deranges the membrane lipid environment during ischaemia. L-Palmitoylcarnitine TFA inhibits KATP channel activity, without affecting the single channel conductance, through interaction with Kir6.2[1].

Product Specifications

Product Name Alternative

BAY-N-7133

UNSPSC

12352211

Target

Endogenous Metabolite; Potassium Channel

Type

Natural Products

Related Pathways

Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/l-palmitoylcarnitine-tfa.html

Purity

98.0

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CCCCCCCCCCCCCCCC(O[C@H](CC([O-])=O)C[N+](C)(C)C)=O.OC(C(F)(F)F)=O

Molecular Formula

C25H46F3NO6

Molecular Weight

513.63

References & Citations

[1]Haruna T, et al. Alteration of the membrane lipid environment by L-palmitoylcarnitine modulates K (ATP) channels in guinea-pig ventricular myocytes. Pflugers Arch. 2000;441 (2-3) :200-207.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Natural Products

Clinical Information

No Development Reported

Isoform

Human Endogenous Metabolite

Available Sizes

Frequently Asked Questions

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