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M3227G (5) ppp (5') Am (triammonium)

M3227G (5) ppp (5') Am triammonium is the triammonium salt form of m3227G (5) ppp (5') Am (HY-164985) . m3227G (5) ppp (5') Am is a specific mRNA molecule structure, which is composed of a 3227-methylguanine (m3227G) cap, a triphosphate group and a 2'-O-methyladenosine. Am is a reversible modification located on the first coding nucleotide near the 5' cap of mRNA, that can affect the stability of mRNA[1].

Product Specifications

UNSPSC

12352005

Target

DNA/RNA Synthesis

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/m3227g-5-ppp-5-am-triammonium.html

Smiles

O=C1C2=C(N([C@H]3[C@H](O)[C@H](O)[C@@H](COP(OP(OP(OC[C@H]4O[C@@H](N(C=N5)C6=C5C(N)=NC=N6)[C@H](OC)[C@@H]4O)(O)=O)(O)=O)([O-])=O)O3)C=[N+]2C)NC(N(C)C)=N1.N.N.N

Molecular Formula

C24H44N13O17P3

Molecular Weight

879.60

References & Citations

[1]Mauer J, et al. Reversible methylation of m6Am in the 5' cap controls mRNA stability. Nature. 2017 Jan 19;541 (7637) :371-375.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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