M3227G (5) ppp (5') Am (triammonium)
M3227G (5) ppp (5') Am triammonium is the triammonium salt form of m3227G (5) ppp (5') Am (HY-164985) . m3227G (5) ppp (5') Am is a specific mRNA molecule structure, which is composed of a 3227-methylguanine (m3227G) cap, a triphosphate group and a 2'-O-methyladenosine. Am is a reversible modification located on the first coding nucleotide near the 5' cap of mRNA, that can affect the stability of mRNA[1].
Product Specifications
UNSPSC
12352005
Target
DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/m3227g-5-ppp-5-am-triammonium.html
Smiles
Molecular Formula
C24H44N13O17P3
Molecular Weight
879.60
References & Citations
[1]Mauer J, et al. Reversible methylation of m6Am in the 5' cap controls mRNA stability. Nature. 2017 Jan 19;541 (7637) :371-375.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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