TXA707
TXA707, the active metabolite of TXA-709, is an FtsZ inhibitor with antibacterial activity. TXA707 is promising for research of S. aureus infections[1][2].
Product Specifications
CAS Number
1609670-89-4
UNSPSC
12352005
Target
Bacterial; Drug Metabolite
Type
Reference compound
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/txa707.html
Purity
99.92
Smiles
O=C(C1=C(F)C(OCC2=NC3=C(S2)N=CC(C(F)(F)F)=C3)=CC=C1F)N
Molecular Formula
C15H8F5N3O2S
Molecular Weight
389.30
References & Citations
[1]Lepak AJ, et al. In Vivo Pharmacodynamic Evaluation of an FtsZ Inhibitor, TXA-709, and Its Active Metabolite, TXA-707, in a Murine Neutropenic Thigh Infection Model. Antimicrob Agents Chemother. 2015 Oct;59 (10) :6568-74. |[2]Kaul M, et al. TXA709, an FtsZ-Targeting Benzamide Prodrug with Improved Pharmacokinetics and Enhanced In Vivo Efficacy against Methicillin-Resistant Staphylococcus aureus. Antimicrob Agents Chemother. 2015 Aug;59 (8) :4845-55.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
LC402220 20 µg
Thioredoxin 2 (TXN2) (NM_012473) Human Over-expression Lysate
Sign In for Pricing
View Details 
PKSV030437 100 µg
Recombinant SARS-CoV-2 Spike RBD (K378N) (His Tag)
Sign In for Pricing
View Details 