Misonidazole
Misonidazole (Ro 7-0582; SR 1354) is a hypoxic tumor cell radiosensitizer[1]. Misonidazole also has antimicrobial effects[2].
Product Specifications
CAS Number
[13551-87-6]
Product Name Alternative
Ro 7-0582; SR 1354
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Bacterial; Parasite
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/misonidazole.html
Purity
98.74
Solubility
10 mM in DMSO
Smiles
COCC(O)CN1C([N+]([O-])=O)=NC=C1
Molecular Formula
C7H11N3O4
Molecular Weight
201.18
Precautions
H302, H315, H319, H335
References & Citations
[1]Bibo Li, et al. Preparation, Characterization, and In Vitro pH-sensitivity Evaluation of Superparamagnetic Iron Oxide Nanoparticle- Misonidazole pH-sensitive Liposomes. Curr Drug Deliv. 2019;16 (3) :254-267. |[2]R C Knight, et al. Mechanism of action of nitroimidazole antimicrobial and antitumour radiosensitizing drugs. Effects of reduced misonidazole on DNA. Int J Radiat Biol Relat Stud Phys Chem Med. 1979 Oct;36 (4) :367-77.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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