Misonidazole

Misonidazole (Ro 7-0582; SR 1354) is a hypoxic tumor cell radiosensitizer[1]. Misonidazole also has antimicrobial effects[2].

Product Specifications

CAS Number

[13551-87-6]

Product Name Alternative

Ro 7-0582; SR 1354

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Bacterial; Parasite

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Infection

Assay Protocol

https://www.medchemexpress.com/misonidazole.html

Purity

98.74

Solubility

10 mM in DMSO

Smiles

COCC(O)CN1C([N+]([O-])=O)=NC=C1

Molecular Formula

C7H11N3O4

Molecular Weight

201.18

Precautions

H302, H315, H319, H335

References & Citations

[1]Bibo Li, et al. Preparation, Characterization, and In Vitro pH-sensitivity Evaluation of Superparamagnetic Iron Oxide Nanoparticle- Misonidazole pH-sensitive Liposomes. Curr Drug Deliv. 2019;16 (3) :254-267. |[2]R C Knight, et al. Mechanism of action of nitroimidazole antimicrobial and antitumour radiosensitizing drugs. Effects of reduced misonidazole on DNA. Int J Radiat Biol Relat Stud Phys Chem Med. 1979 Oct;36 (4) :367-77.