Flumexadol
Flumexadol is a selective and affinity 5-HT2C receptor agonist with a Ki of 25 nM for the (+) -enantiomer of Flumexadol, and is 40-fold selective over the 5-HT2A receptor. Flumexadol is an orally active non-narcotic analgesic[1][2].
Product Specifications
CAS Number
30914-89-7
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/flumexadol.html
Purity
99.86
Solubility
DMSO : 33.33 mg/mL (ultrasonic)
Smiles
FC(C1=CC(C2CNCCO2)=CC=C1)(F)F
Molecular Formula
C11H12F3NO
Molecular Weight
231.22
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
References & Citations
[1]Hache J, et al. The pharmacology of 1841 CERM, a new analgesic. Arzneimittelforschung. 1978;28 (4) :642-5.|[2]Nilsson BM. 5-Hydroxytryptamine 2C (5-HT2C) receptor agonists as potential antiobesity agents. J Med Chem. 2006 Jul 13;49 (14) :4023-34.|[3]Kucharczyk N, et al. Metabolites of 2- (3-trifluoromethylphenyl) tetrahydro-1,4-oxazine (CERM) 1841) in rats and dogs. Xenobiotica. 1979 Nov;9 (11) :703-11.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
5-HT2 Receptor; α-1 microglobulin
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
