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Orforglipron (hemicalcium hydrate)

Orforglipron hemicalcium hydrate (LY3502970 hemicalcium hydrate; GLP-1 receptor agonist 1 hemicalcium hydrate) is the calcium salt hydrate form of Orforglipron (HY-112185) . Orforglipron is an orally active agonist for Glucagon-like peptide-1 receptor (GLP-1R), which exhibits potency in ameliorating the type 2 diabete[1].

Product Specifications

CAS Number

[3008544-96-2]

Product Name Alternative

LY3502970 (hemicalcium hydrate) ; GLP-1 receptor agonist 1 (hemicalcium hydrate)

UNSPSC

12352005

Target

GCGR

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/orforglipron-hemicalcium-hydrate.html

Purity

99.71

Solubility

DMSO : 25 mg/mL (ultrasonic)

Smiles

C[C@@H]1[C@](N2C3=CC=C([C@]4([H])CC(C)(OCC4)C)C=C3C=C2C(N5[C@H](C6=C(N7C(N(C8=CC=C(N(N=C9)C)C9=C8F)C=C7)=O)N(C%10=CC(C)=C(C(C)=C%10)F)N=C6CC5)C)=O)(C(N%11)=NOC%11=O)C1.[0.5].[Ca].O

Molecular Formula

C48H48F2N10O5.1/2Ca.H2O

Molecular Weight

921.02

References & Citations

[1]Pyrazolopyridine derivative having glp-1 receptor agonist effect. WO2018056453A1

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

Phase 3

Available Sizes

Curated Selection

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