Pomalidomide-C7-NH2 (hydrochloride)
Product Specifications
Product Name Alternative
Pomalidomide 4'-alkylC7-amine (hydrochloride)
UNSPSC Description
Pomalidomide-C7-NH2 (Pomalidomide 4'-alkylC7-amine) hydrochloride is an E3 ligase ligand-linker conjugate. Pomalidomide-C7-NH2 hydrochloride can be used for the synthesis of PROTAC[1][2].
Target Antigen
E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
PROTAC
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pomalidomide-c7-nh2-hydrochloride.html
Purity
98.98
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC=C3NCCCCCCCN)=O.[H]Cl
Molecular Weight
422.91
References & Citations
[1]Li Y, et al. Discovery of MD-224 as a First-in-Class, Highly Potent, and Efficacious Proteolysis Targeting Chimera Murine Double Minute 2 Degrader Capable of Achieving Complete and Durable Tumor Regression. J Med Chem. 2019 Jan 24;62(2):448-466.|[2]Si Woo Choi, et al. Hmg-coa reductase degradation inducing compound. Patent, WO2021201577A1.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-131878/Pomalidomide-C7-NH2-hydrochloride-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-131878/Pomalidomide-C7-NH2-hydrochloride-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2446474-05-9
Available Sizes
Curated Selection
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