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Monacolin J

Monacolin J is an inhibitor of cholesterol biosynthesis, and inhibits the activity of HMG-CoA reductase.

Product Specifications

CAS Number

79952-42-4

Product Name Alternative

Antibiotic MB 530A; Lovastatin diol lactone

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Autophagy; HMG-CoA Reductase (HMGCR)

Type

Reference compound

Related Pathways

Autophagy; Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/Monacolin_J.html

Purity

99.22

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C1C[C@H](O)C[C@@H](CC[C@H]2[C@@H](C)C=CC3=C[C@H](C)C[C@H](O)[C@]23[H])O1

Molecular Formula

C19H28O4

Molecular Weight

320.43

Precautions

H302, H315, H319, H335

References & Citations

[1]Endo A, et al. Monacolins J and L, new inhibitors of cholesterol biosynthesis produced by Monascus ruber. J Antibiot (Tokyo) . 1985 Mar;38 (3) :420-2.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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