IFN-γ Antagonist 1 (acetate)

IFN-γ Antagonist 1 (AYCRDGKIGPPKLDIRKEEKQI) acetate is an interferon-γ (IFN-γ) antagonist. IFN-γ Antagonist 1 acetate inhibits IFN-γ-induced HLR/DR antigen expression in cells. IFN-γ Antagonist 1 acetate can be used in researches of diseases with abnormal immune regulation[1].

Product Specifications

UNSPSC

12352209

Target

IFNAR

Type

Peptides

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/ifn-γ-antagonist-1-acetate.html

Purity

99.55

Solubility

DMSO : < 1 mg/mL (ultrasonic) |H2O : 33.33 mg/mL (ultrasonic)

Smiles

O=C([C@H]1N(CCC1)C(CNC([C@H]([C@@H](C)CC)NC([C@H](CCCCN)NC(CNC([C@H](CC(O)=O)NC([C@H](CCCNC(N)=N)NC([C@H](CSCNC(C)=O)NC([C@@H](NC([C@@H](N)C)=O)CC2=CC=C(C=C2)O)=O)=O)=O)=O)=O)=O)=O)=O)N3[C@@H](CCC3)C(N[C@@H](CCCCN)C(N[C@@H](CC(C)C)C(N[C@@H](CC(O)=O)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCCN)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCCCN)C(N[C@@H](CCC(N)=O)C(N[C@H](C(O)=O)[C@@H](C)CC)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O.CC(O)=O

Molecular Formula

C117H198N34O36S

Molecular Weight

2689.10

References & Citations

[1]Seelig GF, et al. Development of a receptor peptide antagonist to human gamma-interferon and characterization of its ligand-bound conformation using transferred nuclear Overhauser effect spectroscopy. J Biol Chem. 1995 Apr 21;270 (16) :9241-9.