6α-Hydroxy-5α-cholestane
6α-Hydroxy-5α-cholestane (5α-Cholestane-3β,6α-diol) is an oxysterol that promotes the production of superoxide anions in SK-N-BE cells at concentrations of 50 μM and 100 μM[1].
Product Specifications
CAS Number
41083-73-2
Product Name Alternative
5α-Cholestane-3β,6α-diol
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
Reactive Oxygen Species (ROS)
Type
Reference compound
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/6α-hydroxy-5α-cholestane.html
Purity
95.8
Smiles
C[C@@]12[C@]3([H])[C@](C[C@@H]([C@@]1([H])C[C@H](CC2)O)O)([H])[C@@]4([H])[C@](CC3)([C@@](CC4)([H])[C@H](C)CCCC(C)C)C
Molecular Formula
C27H48O2
Molecular Weight
404.67
Precautions
H302, H315, H319, H335
References & Citations
[1]Zarrouk, et al. Effects of cholesterol oxides on cell death induction and calcium increase in human neuronal cells (SK-N-BE) and evaluation of the protective effects of docosahexaenoic acid (DHA; C22:6 n-3) . Steroids 99 (Pt B), 238-247 (2015) .
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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