6α-Hydroxy-5α-cholestane

6α-Hydroxy-5α-cholestane (5α-Cholestane-3β,6α-diol) is an oxysterol that promotes the production of superoxide anions in SK-N-BE cells at concentrations of 50 μM and 100 μM[1].

Product Specifications

CAS Number

[41083-73-2]

Product Name Alternative

5α-Cholestane-3β,6α-diol

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Reactive Oxygen Species (ROS)

Type

Reference compound

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/6α-hydroxy-5α-cholestane.html

Purity

95.8

Smiles

C[C@@]12[C@]3([H])[C@](C[C@@H]([C@@]1([H])C[C@H](CC2)O)O)([H])[C@@]4([H])[C@](CC3)([C@@](CC4)([H])[C@H](C)CCCC(C)C)C

Molecular Formula

C27H48O2

Molecular Weight

404.67

Precautions

H302, H315, H319, H335

References & Citations

[1]Zarrouk, et al. Effects of cholesterol oxides on cell death induction and calcium increase in human neuronal cells (SK-N-BE) and evaluation of the protective effects of docosahexaenoic acid (DHA; C22:6 n-3) . Steroids 99 (Pt B), 238-247 (2015) .