Thiomandelic acid
Thiomandelic acid is a broad spectrum inhibitor of Zinc -lactamases[1].
Product Specifications
CAS Number
[4695-09-4]
UNSPSC
12352005
Hazard Statement
H302, H315, H318, H335
Target
Bacterial; Beta-lactamase
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/thiomandelic-acid.html
Purity
95.37
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
O=C(O)C(S)C1=CC=CC=C1
Molecular Formula
C8H8O2S
Molecular Weight
168.21
Precautions
H302, H315, H318, H335
References & Citations
[1]C Mollard, et al. Thiomandelic acid, a broad spectrum inhibitor of zinc beta-lactamases: kinetic and spectroscopic studies. J Biol Chem. 2001 Nov 30;276 (48) :45015-23.|[2]Christian Damblon, et al. The inhibitor thiomandelic acid binds to both metal ions in metallo-beta-lactamase and induces positive cooperativity in metal binding. J Biol Chem. 2003 Aug 1;278 (31) :29240-51.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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