MYCi361
MYCi361 (NUCC-0196361) is a MYC inhibitor with the Kd of 3.2 μM for binding to MYC. MYCi361 (NUCC-0196361) suppresses tumor growth and enhances anti-PD1 immunotherapy[1].
Product Specifications
CAS Number
[2289690-31-7]
Product Name Alternative
NUCC-0196361
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
C-Myc
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/myci361.html
Purity
99.95
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
ClC1=CC=C(COC2=CC=C(C3=CC(C(F)(F)F)=NN3C)C(O)=C2C4=CC(C(F)(F)F)=CC(C(F)(F)F)=C4)C=C1
Molecular Formula
C26H16ClF9N2O2
Molecular Weight
594.86
Precautions
H302, H315, H319, H335
References & Citations
[1]Han H, et al. Small-Molecule MYC Inhibitors Suppress Tumor Growth and Enhance Immunotherapy. Cancer Cell. 2019 Nov 11;36 (5) :483-497.e15.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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