Oxibendazole

Oxibendazole is an effective benzimidazole anthelmintic and is against nema-tode infections. Oxibendazole can induces apoptosis and has anti-cancer and anti-inflammation activities[1][2].

Product Specifications

CAS Number

[20559-55-1]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Apoptosis; Parasite

Type

Reference compound

Related Pathways

Anti-infection; Apoptosis

Applications

COVID-19-immunoregulation

Field of Research

Infection; Cancer

Assay Protocol

https://www.medchemexpress.com/Oxibendazole.html

Purity

99.89

Solubility

DMSO : 5 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C(OC)NC1=NC2=CC=C(OCCC)C=C2N1

Molecular Formula

C12H15N3O3

Molecular Weight

249.27

Precautions

H302, H315, H319, H335

References & Citations

[1]Hahyun Park , et al.Oxibendazole induces apoptotic cell death in proliferating porcine trophectoderm and uterine luminal epithelial cells via mitochondria-mediated calcium disruption and breakdown of mitochondrial membrane potential. Comp Biochem Physiol C Toxicol Pharmacol. 2019 Jun;220:9-19.|[2]Qiaoli Chen, et al. Oxibendazole inhibits prostate cancer cell growth. Oncol Lett. 2018 Feb;15 (2) :2218-2226.