Miravirsen (sodium)

Product Specifications

Product Name Alternative

SPC-3649 (sodium)

UNSPSC Description

Miravirsen sodium is a potent miR-122 inhibitor and inhibits the biogenesis of miR-122. Miravirsen sodium is a 15-nucleotide locked nucleic acid-modified phosphorothioate antisense oligonucleotide. Miravirsen sodium inhibits HCV replication, and can be used in research of HCV infection[1][2].

Target Antigen

MicroRNA

Type

Oligonucleotides

Related Pathways

Epigenetics

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/miravirsen-sodium.html

Purity

98.98

Solubility

10 mM in H2O

Smiles

[Miravirsen (sodium)]

Molecular Weight

5311.90

References & Citations

[1]Luca F R Gebert, et al. Miravirsen (SPC3649) can inhibit the biogenesis of miR-122. Nucleic Acids Res. 2014 Jan;42(1):609-21.|[2]Elmén J, et, al. Antagonism of microRNA-122 in mice by systemically administered LNA-antimiR leads to up-regulation of a large set of predicted target mRNAs in the liver. Nucleic Acids Res. 2008 Mar;36(4):1153-62.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, stored under nitrogen, away from moisture)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-132598A/Miravirsen-sodium-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-132598A/Miravirsen-sodium-SDS-MedChemExpress.pdf

Clinical Information

Phase 2

Available Sizes

Curated Selection

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