3-Methoxytyramine-d4 (hydrochloride)

3-Methoxytyramine-d4 (hydrochloride) is the deuterium labeled 3-Methoxytyramine hydrochloride. 3-Methoxytyramine hydrochloride is an inactive metabolite of dopamine which can activate trace amine associated receptor 1 (TAAR1) [1][2].

Product Specifications

CAS Number

[1216788-76-9]

Product Name Alternative

3-O-methyl Dopamine-d4 (hydrochloride)

UNSPSC

12352005

Hazard Statement

H225, H301+H311+H331, H370

Target

Drug Metabolite; Endogenous Metabolite

Type

Isotope-Labeled Compounds

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Neurological Disease

Purity

98.55

Solubility

DMSO : ≥ 100mg/mL

Smiles

COC1=CC(C([2H])([2H])C([2H])([2H])N)=CC=C1O.Cl

Molecular Formula

C9H10D4ClNO2

Molecular Weight

207.69

Precautions

H225, H301+H311+H331, H370

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Sotnikova TD, et al. The dopamine metabolite 3-methoxytyramine is a neuromodulator. PLoS One. 2010 Oct 18;5 (10) :e13452.|[3]Guldberg HC, et al. Some observations on the estimation of 3-methoxytyramine in brain tissue. Br J Pharmacol. 1971 Aug;42 (4) :505-11.