Anti-Mouse IL-1R Antibody (JAMA-147)

Anti-Mouse IL-1R Antibody (JAMA-147) is an anti-mouse IL-1R IgG2b antibody inhibitor derived from host Armenian Hamster. Anti-Mouse IL-1R Antibody (JAMA-147) diminishes Spp1hi-TAM-mediated T cell suppression. Anti-Mouse IL-1R Antibody (JAMA-147) can be used for the researches of inflammation, metabolic disease and infection, such as diabetes[1][2][3][4].

Product Specifications

CAS Number

[9007-83-4]

UNSPSC

12352203

Hazard Statement

H302, H315, H319, H335

Target

Interleukin Related

Type

Inhibitory Antibodies

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Infection; Metabolic Disease; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/anti-mouse-il-1r-antibody-jama-147.html

Purity

95.00

Solubility

H2O

Smiles

[Anti-MouseIL-1RAntibody(JAMA-147)]

Molecular Weight

(150 kDa)

Precautions

H302, H315, H319, H335

References & Citations

[1]Liu X, et al. NLRP3-mediated IL-1β in regulating the imbalance between Th17 and Treg in experimental autoimmune prostatitis. Sci Rep. 2024 Aug 13;14 (1) :18829.|[2]Lyu A, et al. Evolution of myeloid-mediated immunotherapy resistance in prostate cancer. Nature. 2025 Jan;637 (8048) :1207-1217.|[3]Rahman MJ, et al. Restoration of the type I IFN-IL-1 balance through targeted blockade of PTGER4 inhibits autoimmunity in NOD mice. JCI Insight. 2018 Feb 8;3 (3) :e97843. |[4]Chambers CA, et al. Nitric oxide inhibits interleukin-1-mediated protection against Escherichia coli K1-induced sepsis and meningitis in a neonatal murine model. Immunol Cell Biol. 2021 Jul;99 (6) :596-610.