DMT-5Me-dC (Bz) -CE Phosphoramidite

DMT-5Me-dC (Bz) -CE Phosphoramidite is a chemical structural unit that can be used in solid-phase DNA synthesis. DMT-5Me-dC (Bz) -CE Phosphoramidite can introduce the 5-methylcytidine base into the DNA chain to enhance its stability and binding affinity. DMT-5Me-dC (Bz) -CE Phosphoramidite can be used to construct modified oligonucleotides, especially for constructing locked nucleic acids (LNA) [1].

Product Specifications

CAS Number

[105931-57-5]

UNSPSC

12352005

Hazard Statement

H302

Target

DNA/RNA Synthesis

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/dmt-5me-dc-bz-ce-phosphoramidite.html

Purity

98.36

Solubility

DMSO : 200 mg/mL (ultrasonic)

Smiles

CC(C)N(C(C)C)P(OCCC#N)O[C@@H](C[C@@](N1C(N=C(C(C)=C1)NC(C2=CC=CC=C2)=O)=O)([H])O3)[C@H]3COC(C4=CC=C(C=C4)OC)(C5=CC=CC=C5)C6=CC=C(C=C6)OC

Molecular Formula

C47H54N5O8P

Molecular Weight

847.93

Precautions

H302

References & Citations

[1]Irina V Astakhova, et al. LNA for optimization of fluorescent oligonucleotide probes: improved spectral properties and target binding. Bioconjug Chem. 2011 Apr 20;22 (4) :533-9.