MATE-IN-1
MATE-IN-1 (Compound 31) is an inhibitor of MATE, with EC50 value of 1.8 μM. MATE-IN-1 has antibacterial activity[1].
Product Specifications
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/mate-in-1.html
Solubility
10 mM in DMSO
Smiles
FS(C1=CC(C2=CC=C(CN(C)/C(N(C)C)=N/C#N)C=C2)=CC=C1)(F)(F)(F)F
Molecular Formula
C18H19F5N4S
Molecular Weight
418.43
References & Citations
[1]Shinya S, et al. Pentafluorosulfanyl-substituted biaryl derivatives as MATE-type transporter inhibitors targeting drug-resistant bacteria. Bioorg Med Chem. 2024 Feb 1;99:117606.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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