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MATE-IN-1

MATE-IN-1 (Compound 31) is an inhibitor of MATE, with EC50 value of 1.8 μM. MATE-IN-1 has antibacterial activity[1].

Product Specifications

UNSPSC

12352005

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/mate-in-1.html

Solubility

10 mM in DMSO

Smiles

FS(C1=CC(C2=CC=C(CN(C)/C(N(C)C)=N/C#N)C=C2)=CC=C1)(F)(F)(F)F

Molecular Formula

C18H19F5N4S

Molecular Weight

418.43

References & Citations

[1]Shinya S, et al. Pentafluorosulfanyl-substituted biaryl derivatives as MATE-type transporter inhibitors targeting drug-resistant bacteria. Bioorg Med Chem. 2024 Feb 1;99:117606.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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