OT-R antagonist 2
Product Specifications
UNSPSC Description
OT-R antagonist 2 is a nonpeptide low molecular weight OT-R antagonist. OT-R antagonist 2 inhibitis IP3-Synthesis, rat OT-R (IC50 = 0.33 μM).
IC50 value: 0.33μM
Target: oxytocin receptor
Target Antigen
Oxytocin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/OT-R-antagonist-2.html
Solubility
10 mM in DMSO
Smiles
O=C([C@H](C/1)N(C(C2=CC=C(C3=CC=CC=C3C)C=C2)=O)CC1=N\OC)NC[C@@H](O)C4=CC=CC=C4
Molecular Weight
471.55
References & Citations
[1]Cirillo R, et al. Pharmacology of (2S,4Z)-N-[(2S)-2-hydroxy-2-phenylethyl]-4-(methoxyimino) -1-[(2'-methyl[1,1'-biphenyl]-4-yl)carbonyl]-2-pyrrolidinecarboxamide, a new potent and selective nonpeptide antagonist of the oxytocin receptor. J Pharmacol Exp Ther. 2003 Jul;306(1):253-61.|[2]William Nadler, et al. Method for preparing pyrrolidine oximes. WO/2005082848/A2.|[3]Serge Halazy, et al. Pharmaceutically active pyrrolidine derivatives as bax inhibitors.WO/2001074769/A1.|[4]Serge Halazy, et al. Pharmaceutically active pyrrolidine derivatives as bax inhibitors. WO/2001072705/A1.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-15015A/OT-R-antagonist-2-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-15015A/OT-R-antagonist-2-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
364071-16-9
Available Sizes
Curated Selection
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