Bedaquiline (fumarate) (Standard)

Bedaquiline (fumarate) (Standard) is the analytical standard of Bedaquiline (fumarate) . This product is intended for research and analytical applications. Bedaquiline fumarate, a diarylquinoline antibiotic that targets ATP synthase, is effective for the treatment of Mycobacterium tuberculosis infections.

Product Specifications

CAS Number

[845533-86-0]

Product Name Alternative

R403323 (Standard) ; TMC207 fumarate (Standard) ; R207910 fumarate (Standard)

UNSPSC

12352005

Hazard Statement

H301, H373, H410

Target

Antibiotic; Bacterial; Reference Standards

Type

Reference Standards

Related Pathways

Anti-infection; Others

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/bedaquiline-fumarate-standard.html

Purity

99.98

Smiles

OC(/C=C/C(O)=O)=O.BrC1=CC=C(N=C(OC)C([C@H]([C@@](C2=CC=CC3=C2C=CC=C3)(O)CCN(C)C)C4=CC=CC=C4)=C5)C5=C1

Molecular Formula

C36H35BrN2O6

Molecular Weight

671.58

Precautions

H301, H373, H410

References & Citations

[1]Jang JC, et al. Bedaquiline susceptibility test for totally drug-resistant tuberculosis Mycobacterium tuberculosis. J Microbiol. 2017 Apr 20.|[2]Pang Y, et al. In Vitro Activity of Bedaquiline against Nontuberculous Mycobacteria in China. Antimicrob Agents Chemother. 2017 Apr 24;61 (5) .|[3]Chahine EB, et al. Bedaquiline: a novel diarylquinoline for multidrug-resistant tuberculosis. Ann Pharmacother. 2014 Jan;48 (1) :107-15.