TRAP-14

TRAP-14 (SFLLRNPNDKYEPF) is a synthetic thrombin receptor agonist peptide.

Product Specifications

CAS Number

[137339-65-2]

Product Name Alternative

SFLLRNPNDKYEPF

UNSPSC

12352209

Target

Thrombin

Type

Peptides

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/trap-14.html

Purity

99.94

Solubility

H2O : ≥ 100 mg/mL

Smiles

OC[C@H](N)C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(N)=O)C(N2[C@@H](CCC2)C(N[C@@H](CC(N)=O)C(N[C@@H](CC(O)=O)C(N[C@@H](CCCCN)C(N[C@H](C(N[C@@H](CCC(O)=O)C(N3[C@@H](CCC3)C(N[C@H](C(O)=O)CC4=CC=CC=C4)=O)=O)=O)CC5=CC=C(C=C5)O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O

Molecular Formula

C81H118N20O23

Molecular Weight

1739.92

References & Citations

[1]Sugama Y, et al. Thrombin receptor 14-amino acid peptide mediates endothelial hyperadhesivity and neutrophil adhesion by P-selectin-dependent mechanism. Circ Res. 1992 Oct;71 (4) :1015-9.|[2]Sabo T, et al. Structure-activity studies of the thrombin receptor activating peptide. Biochem Biophys Res Commun. 1992 Oct 30;188 (2) :604-10.|[3]Maruyama Y, et al. Thrombin receptor agonist peptide decreases thrombomodulin activity in cultured human umbilical vein endothelial cells. Biochem Biophys Res Commun. 1994 Mar 30;199 (3) :1262-9.