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CCR7 antagonist 1

CCR7 antagonist 1 (30c) is a dual CXCR2 (IC50 of 11.02 μM) and CCR7 (IC50 of 0.43 μM) antagonist[1].

Product Specifications

UNSPSC

12352005

Target

CXCR

Type

Reference compound

Related Pathways

GPCR/G Protein; Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/ccr7-antagonist-1.html

Purity

99.55

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

CCCCCCSC1=NC(N[C@H](C)CO)=C2N=NNC2=N1

Molecular Formula

C13H22N6OS

Molecular Weight

310.42

References & Citations

[1]Max Van Hoof, et al. Optimization of triazolo[4,5-d]pyrimidines towards human CC chemokine receptor 7 (CCR7) antagonists. Eur J Med Chem. 2023 May 5;251:115240.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, stored under nitrogen)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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