CCR7 antagonist 1
CCR7 antagonist 1 (30c) is a dual CXCR2 (IC50 of 11.02 μM) and CCR7 (IC50 of 0.43 μM) antagonist[1].
Product Specifications
UNSPSC
12352005
Target
CXCR
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/ccr7-antagonist-1.html
Purity
99.55
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
CCCCCCSC1=NC(N[C@H](C)CO)=C2N=NNC2=N1
Molecular Formula
C13H22N6OS
Molecular Weight
310.42
References & Citations
[1]Max Van Hoof, et al. Optimization of triazolo[4,5-d]pyrimidines towards human CC chemokine receptor 7 (CCR7) antagonists. Eur J Med Chem. 2023 May 5;251:115240.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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