Human Motor Neurons (iPSC-derived, Normal)

Wong, J. K., Roselle, A. K., Shue, T. M., Shimshak, S. J., Beaty, J. M., Celestin, N. M., Gao, I., Griffin, R. P., Cudkowicz, M. E., & Sadiq, S. A. (2022) . Apolipoprotein B-100-mediated motor neuron degeneration in sporadic amyotrophic lateral sclerosis. Brain Communications, 4 (4) . https://doi.org/10.1093/braincomms/fcac207 — Learn More Liu B, Li M, Zhang L, Chen Z, Lu P. (2022) . Motor neuron replacement therapy for amyotrophic lateral sclerosis. Neural Regen Res;17:1633-9 — Learn More Liu, Y., Dodart, J., Tran, H., Berkovitch, S., Braun, M., Byrne, M., . . . Brown, R. H. (2021) . Variant-selective stereopure oligonucleotides protect against pathologies associated with c9orf72-repeat expansion in preclinical models. Nature Communications, 12 (1) . doi:10.1038/s41467-021-21112-8 — Learn More Shen, X., Beasley, S., Putman, J. N., Li, Y., Prakash, T. P., Rigo, F., . . . Corey, D. R. (2019) . Efficient electroporation of neuronal cells using synthetic oligonucleotides: Identifying duplex RNA and antisense oligonucleotide activators of Human frataxin expression. RNA, 25 (9), 1118-1129. doi:10.1261/rna.071290.119 — Learn More Gasset-Rosa, F., Lu, S., Yu, H., Chen, C., Melamed, Z., Guo, L., . . . Cleveland, D. W. (2019) . Cytoplasmic TDP-43 de-mixing independent of stress granules drives inhibition of nuclear import, loss of nuclear TDP-43, and cell death. Neuron, 102 (2) . doi:10.1016/j.neuron.2019.02.038 — Learn More Martier, R., Liefhebber, J. M., García-Osta, A., Miniarikova, J., Cuadrado-Tejedor, M., Espelosin, M., . . . Konstantinova, P. (2019) . Targeting rna-mediated toxicity in c9orf72 als and/or ftd by rnai-based gene therapy. Molecular Therapy – Nucleic Acids, 16, 26-37. doi:10.1016/j.omtn.2019.02.001 — Learn More Melamed, Z., López-Erauskin, J., Baughn, M. W., Zhang, O., Drenner, K., Lin, N., Wu, D., . . . Cleveland, D. W. (2019) . Premature polyadenylation-mediated loss of stathmin-2 is a hallmark of tdp-43-dependent neurodegeneration. Nature Neuroscience, 22 (2), 180-190. doi:10.1038/s41593-018-0293-z — Learn More Marei, H. E., Althani, A., Lashen, S., Cenciarelli, C., & Hasan, A. (2017) . Genetically unmatched human Ipsc and Esc Exhibit Equivalent gene expression and neuronal differentiation potential. Scientific Reports, 7 (1) . doi:10.1038/s41598-017-17882-1 — Learn More Danziger, S. A., Miller, L. R., Singh, K., Whitney, G. A., Peskind, E. R., Li, G., . . . Smith, J. J. (2017) . An indicator cell assay for blood-based diagnostics. PLOS ONE, 12 (6) . doi:10.1371/journal.pone.0178608 — Learn More