Phospho-Ask1 (Ser83) Rabbit APC Conjugate

<strong>Phospho-Ask1 (Ser83) Rabbit APC Conjugate </strong>_x000D_ <strong>Catalog number:</strong> B2018681_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 10 ug_x000D_ <strong>Molecular Weight or Concentration:</strong> N/A_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> 2-8°C_x000D_ <strong>Keywords:</strong> Apoptosis signal-regulating kinase 1, Mitogen-activated protein kinase kinase kinase 5, MAPK/ERK kinase kinase 5, MAP3K5, MAPKKK5, MEKK5_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Ge Z, Diao H, Yu M, Ji X, Liu Q, Chang X, Wu Q. Connexin 43 mediates changes in protein phosphorylation in HK-2 cells during chronic cadmium exposure Environ Toxicol Pharmacol. 2017 Jul;53:184-190._x000D_ 2: Zhong D, Liu X, Khuri FR, Sun SY, Vertino PM, Zhou W. LKB1 is necessary for Akt-mediated phosphorylation of proapoptotic proteins Cancer Res. 2008 Sep 15;68(18):7270-7._x000D_ 3: Gu JJ, Wang Z, Reeves R, Magnuson NS. PIM1 phosphorylates and negatively regulates ASK1-mediated apoptosis Oncogene. 2009 Dec 3;28(48):4261-71._x000D_ 4: Esteban-Collado J, Corominas M, Serras F. Nutrition and PI3K/Akt signaling are required for p38-dependent regeneration Development. 2021 Apr 15;148(8):dev197087._x000D_ 5: Ahn J, Won M, Choi JH, Kim YS, Jung CR, Im DS, Kyun ML, Lee K, Song KB, Chung KS. Reactive oxygen species-mediated activation of the Akt/ASK1/p38 signaling cascade and p21(Cip1) downregulation are required for shikonin-induced apoptosis Apoptosis. 2013 Jul;18(7):870-81._x000D_ 6: Yuan ZQ, Feldman RI, Sussman GE, Coppola D, Nicosia SV, Cheng JQ. AKT2 inhibition of cisplatin-induced JNK/p38 and Bax activation by phosphorylation of ASK1: implication of AKT2 in chemoresistance J Biol Chem. 2003 Jun 27;278(26):23432-40._x000D_ 7: Into T, Shibata K. Apoptosis signal-regulating kinase 1-mediated sustained p38 mitogen-activated protein kinase activation regulates mycoplasmal lipoprotein- and staphylococcal peptidoglycan-triggered Toll-like receptor 2 signalling pathways Cell Microbiol. 2005 Sep;7(9):1305-17._x000D_ 8: Beauvais DM, Jung O, Yang Y, Sanderson RD, Rapraeger AC. Syndecan-1 (CD138) Suppresses Apoptosis in Multiple Myeloma by Activating IGF1 Receptor: Prevention by SynstatinIGF1R Inhibits Tumor Growth Cancer Res. 2016 Sep 1;76(17):4981-93._x000D_ 9: Song JJ, Lee YJ. Cross-talk between JIP3 and JIP1 during glucose deprivation: SEK1-JNK2 and Akt1 act as mediators J Biol Chem. 2005 Jul 22;280(29):26845-55._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/17184578">10: Wang Q, Zhang QG, Wu DN, Yin XH, Zhang GY. Neuroprotection of selenite against ischemic brain injury through negatively regulating early activation of ASK1/JNK cascade via activation of PI3K/AKT pathway Acta Pharmacol Sin. 2007 Jan;28(1):19-27. </a>_x000D_ _x000D_ <strong>Products Related to Phospho-Ask1 (Ser83) Rabbit APC Conjugate can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>