Ophiopogonin D'
Ophiopogonin D' is a steroidal saponin and a SIRT1 activator. Ophiopogonin D' can also regulate the activities of transporters OATP1B1 and OATP1B3. Ophiopogonin D' exhibits certain toxicity to tumor cells. Ophiopogonin D' can be used in tumor research[1][2][3].
Product Specifications
CAS Number
65604-80-0
UNSPSC
12352005
Target
OAT; Sirtuin
Type
Natural Products
Related Pathways
Cell Cycle/DNA Damage; Epigenetics; Membrane Transporter/Ion Channel
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ophiopogonin-d-1.html
Purity
99.94
Solubility
Ethanol : 5 mg/mL (ultrasonic)
Smiles
C[C@@]12[C@]3([H])[C@](O[C@]4(CC[C@@H](C)CO4)[C@H]3C)([H])C[C@@]1([H])[C@@]5([H])[C@]([C@@]6(C(C[C@@H](O[C@@]7([H])[C@@H]([C@H]([C@H](O)[C@@H](CO)O7)O[C@@]8([H])[C@@H]([C@H]([C@H](O)CO8)O)O)O[C@@]9([H])[C@@H]([C@@H]([C@@H](O)[C@H](C)O9)O)O)CC6)=CC5)C)([H])CC2
Molecular Formula
C44H70O16
Molecular Weight
855.02
References & Citations
[1]Wang L , et al. Homo-aro-cholestane, furostane and spirostane saponins from the tubers of Ophiopogonjaponicus. Phytochemistry. 2017 Apr;136:125-132.|[2]Wang Y, et al. Specific Turn-On Fluorescent Probe with Aggregation-Induced EmissionCharacteristics for SIRT1 Modulator Screening and Living-Cell Imaging. Anal Chem. 2015;87 (10) :5046-9.|[3]Chen L, et al. Modulation of transporter activity of OATP1B1 and OATP1B3 by the major active components of Radix Ophiopogonis. Xenobiotica. 2019 Oct;49 (10) :1221-1228.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
SIRT1
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC471932-100 1x 100 µL
CD44v4 (Marker of Tumor Metastasis) (rCD44v4/1219), CF647 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
