OSM-SMI-10B

OSM-SMI-10B a derivative of OSM-SMI-10. OSM-SMI-10B significantly reduces OSM-induced STAT3 phosphorylation in cancer cells upon co-incubation with OSM (Oncostatin M) [1].

Product Specifications

UNSPSC

12352005

Target

STAT

Type

Reference compound

Related Pathways

JAK/STAT Signaling; Stem Cell/Wnt

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/osm-smi-10b.html

Purity

99.70

Solubility

DMSO : 250 mg/mL (ultrasonic)

Smiles

O=C(O)/C=C/C1=CC(C2=CC=C(OCO3)C3=C2)=C(C4=CC=C(OCO5)C5=C4)O1

Molecular Formula

C21H14O7

Molecular Weight

378.33

References & Citations

[1]Mass OA, et al. Bioactive recombinant human oncostatin M for NMR-based screening in drug discovery. Sci Rep. 2021 Aug 10;11 (1) :16174.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

STAT3

Available Sizes

Curated Selection

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