BMS-902483
BMS-902483 is a quinuclidine-containing spirooxazolidine that is a partial agonist of the α7 nicotinic acetylcholine receptor (nAChR) . BMS-902483 improves cognitive ability in preclinical rodent models.[1].
Product Specifications
CAS Number
1192810-88-0
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
NAChR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/bms-902483.html
Smiles
C12CCN(CC2)C[C@]13OC(NC4=CC5=C(C=CC=C5)C=N4)=NC3
Molecular Formula
C18H20N4O
Molecular Weight
308.38
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Design and Synthesis of a New Series of 4-Heteroarylamino-1'-azaspiro[oxazole-5, 3’-bicyclo[2.2.2]octanes as α7 Nicotinic Receptor Agonists. 1. Development of Pharmacophore and Early Structure Activity Relationship.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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