N-Acetyl-L-cysteine ethyl ester

N-Acetyl-L-cysteine ethyl ester is an esterified form of N-acetyl-L-cysteine (NAC) . N-Acetyl-L-cysteine ethyl ester exhibits enhanced cell permeability, and produce NAC and cysteine. N-Acetyl-L-cysteine ethyl ester increases circulating hydrogen sulfide (H2S) and can be used as an H2S producer. N-Acetyl-L-cysteine ethyl ester has the potential to substitute NAC as a mucolytic agent, and as a GSH-related antioxidant[1].

Product Specifications

CAS Number

[59587-09-6]

Product Name Alternative

N-Acetylcysteine ethyl ester; NACET

UNSPSC

12352211

Hazard Statement

H302, H312, H332

Target

Reactive Oxygen Species (ROS)

Type

Reference compound

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/n-acetyl-l-cysteine-ethyl-ester.html

Purity

99.87

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

SC[C@@H](C(OCC)=O)NC(C)=O

Molecular Formula

C7H13NO3S

Molecular Weight

191.25

Precautions

H302, H312, H332

References & Citations

[1]Daniela Giustarini, et al. N-Acetylcysteine ethyl ester (NACET) : a novel lipophilic cell-permeable cysteine derivative with an unusual pharmacokinetic feature and remarkable antioxidant potential. Biochem Pharmacol. 2012 Dec 1;84 (11) :1522-33.