Octocrylene (Standard)

Octocrylene (Standard) is the analytical standard of Octocrylene. This product is intended for research and analytical applications. Octocrylene is an organic ultraviolet (UV) filter which absorbs mainly UVB radiation and short UVA wavelengths. Octocrylene has the potential for using in various cosmetic products to either provide an appropriate sun protection factor in sunscreen products or to protect cosmetic formulations from UV radiation[1].

Product Specifications

CAS Number

[6197-30-4]

UNSPSC

12352005

Hazard Statement

H400, H410

Target

Biochemical Assay Reagents; Cytochrome P450; Estrogen Receptor/ERR; PPAR; Reference Standards

Type

Reference Standards

Related Pathways

Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Others; Vitamin D Related/Nuclear Receptor

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/octocrylene-standard.html

Purity

98.08

Smiles

O=C(OCC(CC)CCCC)/C(C#N)=C(C1=CC=CC=C1)\C2=CC=CC=C2

Molecular Formula

C24H27NO2

Molecular Weight

361.48

Precautions

H400, H410

References & Citations

[1]E Berardesca, et al. Review of the safety of octocrylene used as an ultraviolet filter in cosmetics. J Eur Acad Dermatol Venereol. 2019 Nov;33 Suppl 7:25-33.|[2]Vatan Ö, et al. Evaluation of cytotoxic and genotoxic potential of avobenzone and octocrylene on human skin fibroblast cells[J]. All Life, 2023, 16 (1) : 2270171.|[3]Meng Q, et al. Toxic effects of octocrylene on zebrafish larvae and liver cell line (ZFL) [J]. Aquatic Toxicology, 2021, 236: 105843.|[4]Ko H, et al. Sunscreen filter octocrylene is a potential obesogen by acting as a PPARγ partial agonist[J]. Toxicology letters, 2022, 355: 141-149.|[5]de Groot A C, et al. Contact and photocontact allergy to octocrylene: a review[J]. Contact dermatitis, 2014, 70 (4) : 193-204.