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Crenezumab

Crenezumab (MABT 5102A; RG 7412) is a fully humanized anti-Aβ monoclonal antibody that binds multiple forms of Aβ, such as soluble, oligomeric and fibrillar, for use in Alzheimer's disease research[1].

Product Specifications

CAS Number

1095207-05-8

Product Name Alternative

MABT 5102A; RG 7412

UNSPSC

12352203

Target

Amyloid-β

Type

Inhibitory Antibodies

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/crenezumab.html

Purity

99.86

Solubility

10 mM in DMSO

Smiles

[Crenezumab]

Molecular Weight

(143.32 kDa)

References & Citations

[1]S Zampar, et al. N-terminal heterogeneity of parenchymal and vascular amyloid-β deposits in Alzheimer's disease. Neuropathol Appl Neurobiol. 2020 Dec;46 (7) :673-685.

Shipping Conditions

Dry Ice

Storage Conditions

Store at -80°C for 2 years

Scientific Category

Inhibitory Antibodies

Clinical Information

Phase 3

Available Sizes

Frequently Asked Questions

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