Leronlimab
Leronlimab (PRO 140) is a humanized IgG4 anti-CCR5 monoclonal antibody. Leronlimab inhibits CCR5-mediated HIV-1 viral and lung metastasis in mouse tumor models. Leronlimab can be used for the research of HIV nonalcoholic steatohepatitis (NASH) and cancer[1].
Product Specifications
CAS Number
674782-26-4
Product Name Alternative
PRO 140
UNSPSC
12352203
Target
CCR; HIV
Type
Inhibitory Antibodies
Related Pathways
Anti-infection; GPCR/G Protein; Immunology/Inflammation
Applications
COVID-19-anti-virus
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/leronlimab.html
Purity
98.91
Solubility
10 mM in DMSO
Smiles
[Leronlimab]
Molecular Weight
(146.7 kDa)
References & Citations
[1]Jiao X, et al. Leronlimab, a humanized monoclonal antibody to CCR5, blocks breast cancer cellular metastasis and enhances cell death induced by DNA damaging chemotherapy. Breast Cancer Res. 2021 Jan 23;23 (1) :11.
Shipping Conditions
Dry Ice
Storage Conditions
Store at -80°C for 2 years
Scientific Category
Inhibitory Antibodies
Clinical Information
Phase 3
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
LY402344 100 µg
Rabex5 (RABGEF1) (NM_014504) Human Over-expression Lysate
Sign In for Pricing
View Details 
TRC-B285920-50MG 50 mg
(S)-3-Benzyloxycarbonyl-4-(3-oxobutyl)-5-oxazilidinone
Sign In for Pricing
View Details